منابع مشابه
Closed-loop control for pediatric Type 1 diabetes mellitus
Closed-loop clinical trials have resulted in significant advances with continuous glucose monitoring and control systems modulating insulin delivery. Those trials were performed in closely supervised clinical research settings; while adults with Type 1 diabetes were initially targeted, studies in children with Type 1 diabetes have followed in both clinical research units and pediatric diabetes ...
متن کاملClosed-loop insulin delivery for treatment of type 1 diabetes
Type 1 diabetes is one of the most common endocrine problems in childhood and adolescence, and remains a serious chronic disorder with increased morbidity and mortality, and reduced quality of life. Technological innovations positively affect the management of type 1 diabetes. Closed-loop insulin delivery (artificial pancreas) is a recent medical innovation, aiming to reduce the risk of hypogly...
متن کاملA bihormonal closed-loop artificial pancreas for type 1 diabetes.
Automated control of blood glucose (BG) concentration is a long-sought goal for type 1 diabetes therapy. We have developed a closed-loop control system that uses frequent measurements of BG concentration along with subcutaneous delivery of both the fast-acting insulin analog lispro and glucagon (to imitate normal physiology) as directed by a computer algorithm. The algorithm responded only to B...
متن کاملArtificial Pancreas Device Systems for the Closed-Loop Control of Type 1 Diabetes
BACKGROUND Closed-loop artificial pancreas device (APD) systems are externally worn medical devices that are being developed to enable people with type 1 diabetes to regulate their blood glucose levels in a more automated way. The innovative concept of this emerging technology is that hands-free, continuous, glycemic control can be achieved by using digital communication technology and advanced...
متن کاملA Review of Closed-Loop Algorithms for Glycemic Control in the Treatment of Type 1 Diabetes
With the discovery of insulin came a deeper understanding of therapeutic options for one of the most devastating chronic diseases of the modern era, diabetes mellitus. The use of insulin in the treatment of diabetes, especially in those with severe insulin deficiency (type 1 diabetes), with multiple injections or continuous subcutaneous infusion, has been largely successful, but the risk for sh...
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ژورنال
عنوان ژورنال: BMJ
سال: 2011
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.d1911